{"id":63537,"date":"2025-03-30T09:12:40","date_gmt":"2025-03-30T01:12:40","guid":{"rendered":"https:\/\/www.ibnews.com\/cn\/?p=63537"},"modified":"2025-03-30T09:12:40","modified_gmt":"2025-03-30T01:12:40","slug":"%e8%91%9b%e5%85%b0%e7%b4%a0%e5%8f%b2%e5%85%8b%e4%ba%ae%e7%9b%b8%e7%ac%ac34%e5%b1%8a%e4%ba%9a%e5%a4%aa%e8%82%9d%e7%97%85%e5%ad%a6%e4%bc%9a%e5%b9%b4%e4%bc%9a-%e5%85%b1%e8%b5%b4%e4%b9%99%e8%82%9d","status":"publish","type":"post","link":"https:\/\/www.ibnews.com\/cn\/2025\/03\/30\/63537.html","title":{"rendered":"\u845b\u5170\u7d20\u53f2\u514b\u4eae\u76f8\u7b2c34\u5c4a\u4e9a\u592a\u809d\u75c5\u5b66\u4f1a\u5e74\u4f1a 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decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/img2.danews.cc\/upload\/images\/20250330\/1ed73518971eb21c5a832bdbffbfbf93.jpg\" \/><\/p>\n<p style=\"text-align: center;\">\u4faf\u91d1\u6797\u6559\u6388\u5f3a\u8c03\uff0c\u6d88\u9664\u6162\u6027\u4e59\u809d\u5a01\u80c1\u9700\u8981\u201c\u9884\u9632\u201d\u4e0e\u201c\u6cbb\u7597\u201d\u53cc\u7ba1\u9f50\u4e0b<\/p>\n<p><strong>\u201c\u529f\u80fd\u6027\u6cbb\u6108\u201d\u91cd\u5851\u8bca\u7597\u683c\u5c40\uff0c\u52a0\u901f\u53ef\u53ca\u56de\u5e94\u60a3\u8005\u671f\u5f85<\/strong><\/p>\n<p>\u201c\u529f\u80fd\u6027\u6cbb\u6108\u201d\u662f\u56fd\u5185\u5916\u5404\u5927\u6743\u5a01\u9632\u6cbb\u6307\u5357\u63a8\u8350\u7684\u6162\u6027\u4e59\u809d\u7406\u60f3\u6cbb\u7597\u76ee\u6807<sup>[4],<\/sup><sup>[5]<\/sup>\uff0c\u4e0e\u4f1a\u4e13\u5bb6\u4e5f\u5c31\u8fd9\u4e00\u70ed\u70b9\u8bdd\u9898\u5728\u73b0\u573a\u5c55\u5f00\u4e86\u6df1\u5165\u4ea4\u6d41\u3002\u4e13\u5bb6\u4ecb\u7ecd\uff0c\u4e2d\u534e\u533b\u5b66\u4f1a\u53d1\u5e03\u7684\u6700\u65b0\u300a\u6162\u6027\u4e59\u578b\u809d\u708e\u9632\u6cbb\u6307\u5357\uff082022\u5e74\u7248\uff09\u300b<sup>9<\/sup>\u660e\u786e\u6307\u51fa\uff0c\u5bf9\u4e8e\u90e8\u5206\u9002\u5408\u6761\u4ef6\u7684\u6162\u6027\u4e59\u809d\u60a3\u8005\uff0c\u5e94\u8ffd\u6c42\u201c\u529f\u80fd\u6027\u6cbb\u6108\u201d\uff0c\u5176\u5b9a\u4e49\u4e3a\u60a3\u8005\u505c\u836f\u540e\uff0c\u8840\u6db2\u4e2d\u7684\u4e59\u809d\u75c5\u6bd2\u548c\u4e59\u809d\u8868\u9762\u6297\u539f\u6301\u7eed\u68c0\u6d4b\u4e0d\u5230<sup>[6]<\/sup>\uff0c\u610f\u5473\u7740\u60a3\u8005\u65e0\u9700\u518d\u63a5\u53d7\u6cbb\u7597\uff0c\u751f\u6d3b\u8d28\u91cf\u663e\u8457\u6539\u5584\u3002<\/p>\n<p><img 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Theodore\u5148\u751f<\/strong>\u8868\u793a\uff0c\u201cGSK\u59cb\u7ec8\u5fc3\u7cfb\u60a3\u8005\uff0c\u5c06\u60a3\u8005\u7684\u672a\u5c3d\u4e4b\u9700\u4f5c\u4e3a\u7814\u53d1\u521b\u65b0\u7684\u52a8\u529b\u3002\u6211\u4eec\u6df1\u77e5\uff0c\u5e7f\u5927\u4e59\u809d\u60a3\u8005\u8ffd\u6c42\u7684\u4e0d\u4ec5\u4ec5\u662f\u6682\u65f6\u6446\u8131\u75c5\u6bd2\uff0c\u800c\u662f\u4e0d\u88ab\u836f\u7269\u548c\u793e\u4f1a\u6b67\u89c6\u675f\u7f1a\u7684\u5b8c\u6574\u4eba\u751f\u3002\u53ef\u559c\u7684\u662f\uff0c\u968f\u7740\u4ee5ASO\u4e3a\u4ee3\u8868\u7684\u65b0\u578b\u836f\u7269\u4e0d\u65ad\u63a8\u8fdb\u7814\u53d1\uff0c\u2018\u529f\u80fd\u6027\u6cbb\u6108\u2019\u6b63\u5728\u9010\u6b65\u6210\u4e3a\u77ed\u671f\u5185\u53ef\u53ca\u7684\u73b0\u5b9e\u3002\u201d<\/p>\n<p>\u201c\u968f\u7740\u4ee5\u2018\u529f\u80fd\u6027\u6cbb\u6108\u2019\u4e3a\u7814\u7a76\u7ec8\u70b9\u7684ASO\u836f\u7269\u7814\u53d1\u8fdb\u5ea6\u7a33\u6b65\u63a8\u8fdb\uff0c\u76f8\u4fe1\u6162\u6027\u4e59\u809d\u6cbb\u7597\u683c\u5c40\u88ab\u6539\u5199\u7684\u90a3\u4e00\u5929\u5c06\u5f88\u5feb\u5230\u6765\u3002\u8fd9\u7c7b\u521b\u65b0\u6cbb\u7597\u624b\u6bb5\uff0c\u4e0d\u4ec5\u53ef\u4ee5\u5e2e\u52a9\u60a3\u8005\u6446\u8131\u957f\u671f\u670d\u836f\u7684\u8d1f\u62c5\uff0c\u8fd8\u80fd\u663e\u8457\u964d\u4f4e\u540e\u7eed\u75be\u75c5\u8fdb\u5c55\u7684\u98ce\u9669\uff0c\u4e3a\u60a3\u8005\u5e26\u6765\u2018\u65e0\u836f\u65b0\u751f\u2019\u7684\u5e0c\u671b\u3002\u201d<strong>\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u745e\u91d1\u533b\u9662\u611f\u67d3\u79d1\u4e3b\u4efb\u8c22\u9752\u6559\u6388<\/strong>\u8868\u793a\uff0c\u201c\u6211\u4eec\u4e5f\u7531\u8877\u5e0c\u671b\u4ee5ASO\u836f\u7269\u4e3a\u4ee3\u8868\u7684\u7a81\u7834\u6027\u521b\u65b0\u836f\u7269\u80fd\u5c3d\u5feb\u8fdb\u5165\u4e2d\u56fd\u5e76\u5b9e\u73b0\u53ef\u53ca\uff0c\u63a8\u52a8\u2018\u529f\u80fd\u6027\u6cbb\u6108\u2019\u8fd9\u4e00\u7406\u60f3\u6cbb\u7597\u76ee\u6807\u8d70\u8fdb\u5e7f\u5927\u60a3\u8005\u7684\u73b0\u5b9e\uff0c\u4e3a\u4e2d\u56fd\u2018\u6d88\u9664\u4e59\u809d\u2019\u7684\u613f\u666f\u6dfb\u7816\u52a0\u74e6\u3002\u201d<\/p>\n<p><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/img2.danews.cc\/upload\/images\/20250330\/94c18fb5f11a77196f4dad88d90e1fa4.jpg\" \/><\/p>\n<p style=\"text-align: center;\">\u8c22\u9752\u6559\u6388\u671f\u5f85\u4e59\u809d\u7a81\u7834\u6027\u521b\u65b0\u836f\u7269\u80fd\u5c3d\u5feb\u60e0\u53ca\u4e2d\u56fd\u60a3\u8005<\/p>\n<p><strong>\u98ce\u96e8\u540c\u884c\u4e09\u5341\u5e74\uff0c\u4ee5\u4e2d\u56fd\u5b9e\u8df5\u52a9\u63a8\u5168\u7403\u201c\u6cbb\u6108\u672a\u6765\u201d<\/strong><\/p>\n<p>GSK\u4f5c\u4e3a\u624e\u6839\u4e2d\u56fd\u7684\u5168\u7403\u75c5\u6bd2\u6027\u809d\u708e\u9886\u57df\u521b\u65b0\u5f15\u9886\u8005\uff0c\u5df2\u5728\u4e2d\u56fd\u4e59\u809d\u75be\u75c5\u9886\u57df\u6df1\u801530\u4f59\u5e74\uff0c\u5728\u8fd9\u4e00\u8fdb\u7a0b\u4e2d\u59cb\u7ec8\u6df1\u5ea6\u7ed1\u5b9a\u56fd\u5bb6\u516c\u5171\u536b\u751f\u6218\u7565\uff0c\u6301\u7eed\u52a9\u529b\u201c\u5065\u5eb7\u4e2d\u56fd2030\u6218\u7565\u201d\u7684\u75c5\u6bd2\u6027\u809d\u708e\u653b\u575a\u76ee\u6807\uff0c\u5e76\u4e0d\u65ad\u63a2\u7d22\u524d\u6cbf\u7684\u521b\u65b0\u7597\u6cd5\uff0c\u4ee5\u63a8\u52a8\u6162\u6027\u4e59\u809d\u201c\u529f\u80fd\u6027\u6cbb\u6108\u201d\u76ee\u6807\u7684\u5b9e\u73b0\u3002<\/p>\n<p><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/img2.danews.cc\/upload\/images\/20250330\/0aad27d11361daf840120a0ec996f33d.jpg\" \/><\/p>\n<p style=\"text-align: center;\">\u4f59\u6167\u660e\u5973\u58eb\u5f3a\u8c03GSK\u5c06\u59cb\u7ec8\u4e0e\u4e2d\u56fd\u4f19\u4f34\u540c\u884c\uff0c\u4e3a\u521b\u9020\u201c\u6ca1\u6709\u4e59\u809d\u7684\u672a\u6765\u201d\u4e0d\u61c8\u52aa\u529b<\/p>\n<p>\u201c\u4f5c\u4e3a\u5168\u7403\u4e59\u809d\u9632\u6cbb\u9886\u57df\u7684\u5148\u884c\u8005\uff0cGSK\u59cb\u7ec8\u5c06\u52a9\u529b\u5b9e\u73b0\u2018\u6ca1\u6709\u4e59\u809d\u7684\u672a\u6765\u2019\u89c6\u4e3a\u5df1\u4efb\uff0c\u4e0d\u4ec5\u6301\u7eed\u63a8\u52a8\u4e59\u809d\u6297\u75c5\u6bd2\u836f\u7269\u7684\u521b\u65b0\u7814\u53d1\uff0c\u66f4\u81f4\u529b\u4e8e\u643a\u624b\u5404\u65b9\u6784\u5efa\u2018\u7b5b\u67e5-\u6cbb\u7597-\u6cbb\u6108\u2019\u4e09\u4f4d\u4e00\u4f53\u7684\u95ed\u73af\u751f\u6001\uff0c\u4e3a\u5e7f\u5927\u4e2d\u56fd\u60a3\u8005\u5e26\u6765\u5207\u5b9e\u7684\u798f\u7949\u3002\u201d<strong>GSK\u526f\u603b\u88c1\u3001\u4e2d\u56fd\u603b\u7ecf\u7406\u4f59\u6167\u660e\u5973\u58eb<\/strong>\u8868\u793a\uff0c\u201c\u6211\u4eec\u5c06\u59cb\u7ec8\u4e0e\u4e2d\u56fd\u53ca\u5168\u7403\u4f19\u4f34\u7d27\u5bc6\u5408\u4f5c\uff0c\u4ee5\u4e2d\u56fd\u7ecf\u9a8c\u4e3a\u84dd\u672c\uff0c\u52a9\u529b\u6253\u9020\u5168\u7403\u809d\u75c5\u9632\u6cbb\u7f51\u7edc\uff0c\u4ee5\u2018\u4e2d\u56fd\u65b9\u6848\u2019\u52a0\u901f\u5168\u7403\u6d88\u9664\u75c5\u6bd2\u6027\u809d\u708e\u7684\u8fdb\u7a0b\u3002\u8ba9\u6211\u4eec\u643a\u624b\u5e76\u8fdb\uff0c\u4e3a\u521b\u9020\u4e00\u4e2a\u6ca1\u6709\u4e59\u809d\u7684\u672a\u6765\u800c\u4e0d\u61c8\u52aa\u529b\u3002\u201d<\/p>\n<ol>\n<li id=\"footnote-1\">Hui Z., Yu W., et al, New Progress in HBV Control and the Cascade of Health Care for People Living with HBV in China: Evidence from the Fourth National Serological Survey, 2020. The Lancet Regional Health &#8211; Western Pacific. Volume 51, 101193, October 2024\u00a0\u2191<\/li>\n<li id=\"footnote-2\">Yan R, Sun M, Yang H, Du S, Sun L, Mao Y. 2024 latest report on hepatitis B virus epidemiology in China: current status, changing trajectory, and challenges. Hepatobiliary Surg Nutr 2025;14(1):66-77. doi: 10.21037\/hbsn-2024-754 https:\/\/hbsn.amegroups.org\/article\/view\/133540\/html\u00a0\u2191<\/li>\n<li id=\"footnote-3\">Zheng R, Qu C, Zhang S, Zeng H, Sun K, Gu X, Xia C, Yang Z, Li H, Wei W, Chen W, He J. Liver cancer incidence and mortality in China: Temporal trends and projections to 2030. Chin J Cancer Res. 2018 Dec;30(6):571-579. doi: 10.21147\/j.issn.1000-9604.2018.06.01. PMID: 30700925; PMCID: PMC6328503.\u00a0\u2191<\/li>\n<li id=\"footnote-4\">EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. J Hepatol 2017;67(2):370\u2013398. doi:10.1016\/j.jhep.2017.03.021.\u00a0<a href=\"http:\/\/articlef.yulepops.com\/article\/m-292\/1\/512202503300241415997604.html#footnote-ref-4\">\u2191<\/a><\/li>\n<li id=\"footnote-5\">\u4e2d\u534e\u533b\u5b66\u4f1a\u809d\u75c5\u5b66\u5206\u4f1a,\u4e2d\u534e\u533b\u5b66\u4f1a\u611f\u67d3\u75c5\u5b66\u5206\u4f1a. \u6162\u6027\u4e59\u578b\u809d\u708e\u9632\u6cbb\u6307\u5357(2022\u5e74\u7248)[J]. \u4e2d\u534e\u4e34\u5e8a\u611f\u67d3\u75c5\u6742\u5fd7,2022,15(06)\uff1a401-427. DOI:10.3760\/cma.j.issn.1674-2397.2022.06.001\u00a0\u2191<\/li>\n<li id=\"footnote-6\">\u4e2d\u534e\u533b\u5b66\u4f1a\u611f\u67d3\u75c5\u5b66\u5206\u4f1a\uff0c\u4e2d\u534e\u533b\u5b66\u4f1a\u809d\u75c5\u5b66\u5206\u4f1a. \u6162\u6027\u4e59\u578b\u809d\u708e\u4e34\u5e8a\u6cbb\u6108\uff08\u529f\u80fd\u6027\u6cbb\u6108\uff09\u4e13\u5bb6\u5171\u8bc6\uff3bJ\uff3d. \u4e34\u5e8a\u809d\u80c6\u75c5\u6742\u5fd7, 2019, 35(8): 1693-1701.\u00a0\u2191<\/li>\n<li id=\"footnote-7\">\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3. (2023). \u6162\u6027\u4e59\u578b\u809d\u708e\u75c5\u6bd2\u611f\u67d3\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u6280\u672f\u6307\u5bfc\u539f\u5219. \u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u516c\u544a\u901a\u544a. \u53d6\u81ea https:\/\/www.cde.org.cn\/main\/news\/viewInfoCommon\/5bebddb98aae85a980181683a910788e\u00a0\u2191<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<div class=\"mh-excerpt\"><p>2025\u5e743\u670828\u65e5\uff0c\u5728\u7b2c34\u5c4a\u4e9a\u592a\u809d\u75c5\u5b66\u4f1a\uff08APASL\uff09\u5e74\u4f1a\u4e0a\uff0c\u845b\u5170\u7d20\u53f2\u514b\uff08GSK\uff09\u4e3e\u529e\u201c\u52a0\u901f\u5411\u6cbb\u6108\uff0c\u5171\u8d742030\u4f7f\u547d\u201d\u521b\u65b0\u4e13\u573a\u6d3b\u52a8\u3002\u672c\u6b21\u6d3b\u52a8\u6c47\u805a\u5168\u7403\u9876\u5c16\u4e34\u5e8a <a class=\"mh-excerpt-more\" href=\"https:\/\/www.ibnews.com\/cn\/2025\/03\/30\/63537.html\" title=\"\u845b\u5170\u7d20\u53f2\u514b\u4eae\u76f8\u7b2c34\u5c4a\u4e9a\u592a\u809d\u75c5\u5b66\u4f1a\u5e74\u4f1a \u5171\u8d74\u4e59\u809d\u6cbb\u6108\u65b0\u5f81\u7a0b\">[&#8230;]<\/a><\/p>\n<\/div>","protected":false},"author":27,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[119],"tags":[],"class_list":{"0":"post-63537","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-bio-pharmaceuticals"},"_links":{"self":[{"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/posts\/63537","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/comments?post=63537"}],"version-history":[{"count":1,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/posts\/63537\/revisions"}],"predecessor-version":[{"id":63538,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/posts\/63537\/revisions\/63538"}],"wp:attachment":[{"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/media?parent=63537"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/categories?post=63537"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/tags?post=63537"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}