{"id":25038,"date":"2021-06-16T11:37:18","date_gmt":"2021-06-16T03:37:18","guid":{"rendered":"http:\/\/www.businessnews.cn\/?p=25038"},"modified":"2021-06-16T11:37:18","modified_gmt":"2021-06-16T03:37:18","slug":"%e8%8d%a3%e6%b3%bd%e7%94%9f%e7%89%a9%e9%9b%86%e5%9b%a2%e5%90%af%e5%8a%a8ipo%e4%b8%8a%e5%b8%82%e8%be%85%e5%af%bc%ef%bc%8c%e4%b8%93%e6%b3%a8%e7%bb%86%e8%83%9e%e4%b8%8e%e5%9f%ba%e5%9b%a0%e6%8a%80","status":"publish","type":"post","link":"https:\/\/www.ibnews.com\/cn\/2021\/06\/16\/25038.html","title":{"rendered":"\u8363\u6cfd\u751f\u7269\u96c6\u56e2\u542f\u52a8IPO\u4e0a\u5e02\u8f85\u5bfc\uff0c\u4e13\u6ce8\u7ec6\u80de\u4e0e\u57fa\u56e0\u6280\u672f\u8f6c\u5316"},"content":{"rendered":"

2021\u5e746\u67088\u65e5\uff0c\u56fd\u5185\u9886\u5148\u7684\u7ec6\u80de\u4e0e\u57fa\u56e0\u6280\u672f\u5e73\u53f0\u578b\u516c\u53f8\uff0c\u676d\u5dde\u8363\u6cfd\u751f\u7269\u79d1\u6280\u96c6\u56e2\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u8363\u6cfd\u96c6\u56e2\u201d\uff09\u62df\u9996\u6b21\u516c\u5f00\u53d1\u884c\u80a1\u7968\u5e76\u5728\u5883\u5185\u8bc1\u5238\u4ea4\u6613\u6240\u4e0a\u5e02\uff0c\u76ee\u524d\u5df2\u540c\u56fd\u91d1\u8bc1\u5238\u80a1\u4efd\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u56fd\u91d1\u8bc1\u5238\u201d\uff09\u3001\u7acb\u4fe1\u4f1a\u8ba1\u5e08\u4e8b\u52a1\u6240\u3001\u56fd\u6d69\u5f8b\u5e08\uff08\u4e0a\u6d77\uff09\u4e8b\u52a1\u6240\u7b7e\u7f72\u4e0a\u5e02\u8f85\u5bfc\u534f\u8bae\u3002<\/p>\n

 <\/p>\n

<\/p>\n

\u8363\u6cfd\u96c6\u56e2\u6210\u7acb\u4e8e2014\u5e74\uff0c\u662f\u4e00\u5bb6\u4e13\u4e1a\u4ece\u4e8b\u5c16\u7aef\u751f\u547d\u79d1\u5b66\u6280\u672f\u5f00\u53d1\u4e0e\u5e94\u7528\u8f6c\u5316\u7684\u5e73\u53f0\u578b\u4f01\u4e1a\uff0c\u81f4\u529b\u4e8e\u7ec6\u80de\u4e0e\u57fa\u56e0\u6cbb\u7597\u6280\u672f\u5f00\u53d1\u548c\u4e34\u5e8a\u5e94\u7528\u8f6c\u5316\u3001\u4eba\u7c7b\u751f\u547d\u6837\u672c\u5e93\u5efa\u8bbe\u3001\u751f\u7269\u5236\u836f\u59d4\u6258\u7814\u53d1\u670d\u52a1\u3001\u518d\u751f\u533b\u5b66\u7b49\u591a\u4e2a\u4e3b\u8425\u4e1a\u52a1\uff0c\u516c\u53f8\u5165\u9009\u4e2d\u56fd\u533b\u836f\u521b\u65b050\u5f3a\u4f01\u4e1a\uff0c\u5e76\u83b7\u5f97\u56fd\u5bb6\u9ad8\u65b0\u6280\u672f\u4f01\u4e1a\u8ba4\u8bc1\u3002<\/p>\n

\u7ecf\u8fc7\u591a\u5e74\u53d1\u5c55\uff0c\u8363\u6cfd\u96c6\u56e2\u5728\u4e0a\u6d77\u3001\u5317\u4eac\u3001\u676d\u5dde\u7b49\u5730\u5efa\u6709\u591a\u4e2a\u7b26\u5408GMP\u6807\u51c6\u7684\u7ec6\u80de\u4e0e\u57fa\u56e0\u836f\u7269\u5f00\u53d1\u5b9e\u9a8c\u5ba4\uff0c\u76ee\u524d\u9488\u5bf9\u809d\u786c\u5316\u3001\u8f6f\u9aa8\u7f3a\u635f\u3001\u80bf\u7624\u3001\u5148\u5929\u6027\u5fc3\u808c\u75c5\u7b49\u91cd\u5927\u75be\u75c5\u5f00\u53d1\u4e86\u591a\u79cd\u7ec6\u80de\u4e0e\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u7ba1\u7ebf\u3002\u540c\u65f6\u56f4\u7ed5\u7ec6\u80de\u4e0e\u57fa\u56e0\u6280\u672f\u9886\u57df\uff0c\u8054\u5408\u56fd\u5185\u5916\u591a\u4e2a\u673a\u6784\u5171\u5efa\u4e86\u6280\u672f\u8f6c\u5316\u5e73\u53f0\u548c\u4e34\u5e8a\u7814\u7a76\u4e2d\u5fc3\u3002\u7387\u5148\u4e0e\u5317\u4eac\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u8054\u5408\u5f00\u5c55\u5168\u7403\u9996\u4e2a\u5916\u5468\u8840\u5e72\u7ec6\u80de\u6cbb\u7597\u8f6f\u9aa8\u7f3a\u635f\u9879\u76ee\uff1b\u4e0e\u6d59\u6c5f\u5927\u5b66\u7eb3\u7c73\u7814\u7a76\u9662\u6210\u7acb\u4e86\u201c\u751f\u7269\u533b\u5b66\u4e0e\u6280\u672f\u8f6c\u5316\u8054\u5408\u7814\u53d1\u4e2d\u5fc3\u201d\uff1b\u4e0e\u590d\u65e6\u5927\u5b66\u5e72\u7ec6\u80de\u57fa\u56e0\u7f16\u8f91\u5b9e\u9a8c\u5ba4\u5728\u56fd\u9645\u4e0a\u9996\u6b21\u5f00\u5c55\u9057\u4f20\u6027\u5fc3\u808c\u75c5\u7684\u57fa\u56e0\u6cbb\u7597\u7814\u7a76\uff1b\u4e0e\u4e0a\u6d77\u4e2d\u533b\u836f\u5927\u5b66\u9644\u5c5e\u66d9\u5149\u533b\u9662\u5171\u5efa\u201c\u5e72\u7ec6\u80de\u4e34\u5e8a\u7814\u7a76\u4e2d\u5fc3\u201d; \u4e0e\u4e2d\u56fd\u8ba1\u91cf\u5927\u5b66\u5171\u5efa\u4e86\u201c\u5e72\u7ec6\u80de\u5236\u5242\u6807\u51c6\u5316\u7814\u7a76\u4e2d\u5fc3\u201d; \u4e0e\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u8054\u5408\u5f00\u5c55\u65b0\u578b\u975e\u75c5\u6bd2\u8f7d\u4f53\u5728\u57fa\u56e0\u6cbb\u7597\u4e2d\u7684\u5e94\u7528\u9879\u76ee; \u4e0e\u4e1c\u5357\u5927\u5b66\u5f00\u5c55\u4e86\u9057\u4f20\u6027\u8033\u804b\u7684\u57fa\u56e0\u6cbb\u7597\u9879\u76ee; \u4e0e\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u524d\u4e3b\u5e2d\u3001\u725b\u6d25\u5927\u5b66 Walter Bodmer \u9662\u58eb\u56e2\u961f\uff0c\u8bfa\u8d1d\u5c14\u5956\u5f97\u4e3b Brian David Josephson \u6559\u6388\u56e2\u961f\u5f00\u5c55\u4e86\u591a\u4e2a\u751f\u7269\u533b\u836f\u6280\u672f\u8f6c\u5316\u5408\u4f5c\u3002<\/p>\n

\u8363\u6cfd\u96c6\u56e2\u8fd1\u5e74\u6765\u5f15\u8fdb\u4e86\u4e00\u6279\u4e16\u754c\u7ea7\u7684\u4f18\u79c0\u79d1\u5b66\u5bb6\u56e2\u961f\uff0c\u6ee1\u8db3\u4ece\u57fa\u7840\u7814\u7a76\u5230\u4e34\u5e8a\u5e94\u7528\u6240\u9700\u7684\u5168\u65b9\u4f4d\u56e2\u961f\u3002\u7ecf\u8fc7\u591a\u5e74\u7814\u7a76\u79ef\u7d2f\uff0c\u76ee\u524d\u5df2\u5efa\u6210\u4e86\u5168\u7403\u9886\u5148\u7684\u5916\u5468\u8840\u5e72\u7ec6\u80de\uff08RZ-PBMSCs\uff09\u6280\u672f\u5e73\u53f0\u3001\u4eba\u5916\u5468\u8840\u514d\u75ab\u7ec6\u80de\u4e9a\u7fa4\uff08RZ-PBIC\uff09\u6280\u672f\u5e73\u53f0\u3001\u57fa\u56e0\u78b1\u57fa\u7f16\u8f91\u5668\uff08RZ- Base Editor\uff09\u6280\u672f\u5e73\u53f0\u7b49\u591a\u4e2a\u7ec6\u80de\u4e0e\u57fa\u56e0\u6280\u672f\u4f53\u7cfb\u5e73\u53f0\u3002\u57fa\u4e8e\u4ee5\u4e0a\u5e73\u53f0\u4f18\u52bf\uff0c\u8363\u6cfd\u96c6\u56e2\u65d7\u4e0b\u5f00\u53d1\u4e86\u5b89\u5168\u6027\u66f4\u597d\u3001\u6cbb\u7597\u66f4\u6709\u9488\u5bf9\u6027\u7684RZ-s001PbMsc\u79fb\u690d\u6280\u672f\u3001RZ-s002PbMsc\u79fb\u690d\u6280\u672f\u3001RZ-i003Pbic \u7ec6\u80de\u6ce8\u5c04\u6db2\u3001RZ-i005PBic\u7ec6\u80de\u6ce8\u5c04\u6db2\u3001RZ-g007BE\u57fa\u56e0\u6ce8\u5c04\u6db2\u7b49\u4e00\u7cfb\u5217\u7ec6\u80de\u4e0e\u57fa\u56e0\u7597\u6cd5\u7ba1\u7ebf\u3002\u9488\u5bf9\u4ee5\u4e0a\u6280\u672f\u4ea7\u54c1\u7ba1\u7ebf\uff0c\u8363\u6cfd\u96c6\u56e2\u65d7\u4e0b\u9879\u76ee\u516c\u53f8\u5171\u7533\u8bf7\u4e86\u56db\u5341\u4f59\u9879\u53d1\u660e\u4e13\u5229\uff0c\u6570\u5341\u9879\u7814\u7a76\u6210\u679c\u5728\u300aMolecular Therapy Nucleic Acids\u300b\u3001\u300aFrontiersin Genetics\u300b\u3001\u300aFrontiers in Oncology\u300b\u7b49\u56fd\u9645\u77e5\u540d\u5b66\u672f\u671f\u520a\u4e0a\u53d1\u8868\u3002<\/p>\n

<\/p>\n

<\/p>\n

\u8363\u6cfd\u96c6\u56e2\u8463\u4e8b\u957f\u9648\u76f8\u6ce2\u535a\u58eb\u4e0e\u5317\u4eac\u5927\u5b66\u5e38\u52a1\u526f\u6821\u957f\u3001\u5317\u4eac\u5927\u7b2c\u4e09\u533b\u9662\u9662\u957f\u4e54\u6770\u9662\u58eb\u7b7e\u7f72\u201c\u5916\u5468\u8840\u5e72\u7ec6\u80de\u53ca\u76f8\u5173\u7ec4\u7ec7\u5de5\u7a0b\u6750\u6599\u201d\u00a0\u79d1\u6280\u6210\u679c\u8f6c\u5316\u5408\u4f5c\u534f\u8bae\u3002<\/p>\n

\u5176\u4e2dRZ-s001PbMsc\u7cfb\u5217\u4ea7\u54c1\u6280\u672f\u7ba1\u7ebf\u662f\u8363\u6cfd\u96c6\u56e2\u4e0e\u5317\u4eac\u5927\u5b66\u8fd0\u52a8\u533b\u5b66\u7814\u7a76\u6240\u8054\u5408\u5f00\u53d1\uff0c\u5e76\u5728\u5317\u4eac\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u5f00\u5c55\u4e34\u5e8a\u7814\u7a76\u4e0e\u5e94\u7528\uff0c\u8be5\u9879\u76ee\u4e3b\u8981\u662f\u5229\u7528\u60a3\u8005\u81ea\u4f53\u5916\u5468\u8840\u5e72\u7ec6\u80de\u6cbb\u7597\u4fee\u590d\u819d\u5173\u8282\u91cd\u5ea6\u8f6f\u9aa8\u635f\u4f24\uff0c RZ-s001PbMsc\u8010\u7f3a\u6c27\u4f18\u52bf\u548c\u6210\u8f6f\u9aa8\u80fd\u529b\uff0c\u540c\u65f6\u5177\u5907\u975e\u5e38\u597d\u7684\u5b89\u5168\u6027\uff0c\u5c06\u4e3a\u96be\u6cbb\u6027\u8fd0\u52a8\u521b\u4f24\u63d0\u4f9b\u7a81\u7834\u6027\u6cbb\u6108\u7597\u6cd5\uff0c\u6709\u671b\u6210\u4e3a\u56fd\u5185\u5e72\u7ec6\u80de\u9886\u57df\u9996\u4e2a\u4ea7\u4e1a\u5316\u6536\u8d39\u9879\u76ee\u3002RZ-s002PbMscs\u662f\u4e00\u6b3e\u9488\u5bf9\u5931\u4ee3\u507f\u671f\u809d\u786c\u5316\u7684\u7ec6\u80de\u6280\u672f\u7597\u6cd5\uff0c\u7ecf\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u663e\u793a\u8be5\u7597\u6cd5\u5177\u6709\u975e\u5e38\u597d\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\uff0c\u5404\u9879\u6307\u6807\u5f97\u5230\u660e\u663e\u6539\u5584\uff0c\u809d\u75c5\u75c5\u60c5\u53ef\u4ee5\u5f97\u5230\u6709\u6548\u63a7\u5236\uff0c\u8be5\u9879\u76ee\u53ef\u4f5c\u4e3a\u809d\u79fb\u690d\u66ff\u4ee3\u6027\u7597\u6cd5\u3002<\/p>\n

RZ-i003Pbic\u3001RZ-i004Pbic\u7ec6\u80de\u6ce8\u5c04\u6db2\u662f\u4e00\u79cd\u9488\u5bf9\u80bf\u7624\u8f6c\u79fb\u548c\u590d\u53d1\u7684\u514d\u75ab\u7ec6\u80de\u7597\u6cd5\uff0c\u8fd9\u4e24\u79cd\u514d\u75ab\u7ec6\u80de\u6ce8\u5c04\u6db2\u53ef\u6709\u6548\u6e05\u9664\u4f53\u5185\u5faa\u73af\u80bf\u7624\u5e72\u7ec6\u80de\uff0c\u7531\u4e8e\u8be5\u7ec6\u80de\u4e9a\u7fa4\u5728\u4f53\u5185\u542b\u91cf\u6781\u4f4e\uff0c\u4e14\u4f53\u5916\u8bf1\u5bfc\u6269\u589e\u96be\u5ea6\u6781\u5927\uff0c\u56e0\u6b64\u56fd\u9645\u4e0a\u6781\u5c11\u6709\u4f01\u4e1a\u80fd\u591f\u5f00\u5c55\u8be5\u7ec6\u80de\u7597\u6cd5\u7684\u4ea7\u54c1\u7814\u53d1\uff0c\u8363\u6cfd\u96c6\u56e2\u65d7\u4e0bRZ-PBIC\u6280\u672f\u5e73\u53f0\u53ef\u5229\u7528\u4e0d\u540c\u6d53\u5ea6\u6bd4\u4f8b\u7ec6\u80de\u56e0\u5b50\uff0c\u5236\u5907\u51fa\u8d85\u9ad8\u7eaf\u5ea6\u7684\u514d\u75ab\u7ec6\u80de\u5236\u5242\u4ea7\u54c1\uff0c\u8be5\u7ec6\u80de\u7597\u6cd5\u5177\u6709\u6bd4\u5e38\u89c4\u514d\u75ab\u7ec6\u80de\u66f4\u5f3a\u7684\u6297\u80bf\u7624\u6548\u5e94\uff0c\u56e0\u6b64\u53ef\u4ee5\u4f5c\u4e3a\u80bf\u7624\u75be\u75c5\u4e00\u79cd\u5168\u65b0\u7684\u6cbb\u7597\u624b\u6bb5\u3002<\/p>\n

RZ-g007BE\u57fa\u56e0\u6ce8\u5c04\u6db2\u662f\u56fd\u9645\u4e0a\u9996\u4e2a\u5229\u7528\u5355\u78b1\u57fa\u57fa\u56e0\u7f16\u8f91\u5668\u6280\u672f\u6cbb\u7597\u9057\u4f20\u6027\u5fc3\u808c\u75c5\u7684\u4ea7\u54c1\uff0c\u76f8\u6bd4\u4f20\u7edf\u7684CRISPR\/Cas\u7cfb\u7edf\uff0cRZ- Base Editor\u7cfb\u7edf\u5177\u6709\u4e0d\u5f62\u6210\u53cc\u94feDNA\u65ad\u88c2\uff08DSB\uff09\u3001\u65e0\u9700\u4f9b\u4f53DNA\u6a21\u677f\u4ee5\u53ca\u4f4e\u8131\u9776\u6548\u5e94\u7684\u4f18\u52bf\uff0c\u901a\u8fc7\u5b9a\u70b9\u4fee\u590d\u9057\u4f20\u6027\u5fc3\u808c\u75c5\u7684\u57fa\u56e0\u7a81\u53d8\uff0c\u6709\u671b\u4ece\u6839\u672c\u4e0a\u7ea0\u6b63\u60a3\u8005\u7684\u9057\u4f20\u4fe1\u606f\uff0c\u5177\u6709\u91cd\u5927\u7684\u4e34\u5e8a\u5e94\u7528\u6f5c\u529b\u3002<\/p>\n

<\/p>\n

\u8363\u6cfd\u96c6\u56e2\u79c9\u627f \u201c\u7ec6\u80de\u4e0e\u57fa\u56e0\u6280\u672f\u9020\u798f\u4eba\u7c7b\u201d\uff0c\u52a9\u529b\u4e2d\u56fd\u751f\u7269\u521b\u65b0\u836f\u4ea7\u4e1a\u8fdb\u6b65\uff0c\u5207\u5b9e\u63a8\u52a8\u751f\u547d\u79d1\u6280\u6210\u679c\u8f6c\u5316\uff0c\u5b9e\u73b0\u751f\u547d\u79d1\u6280\u60e0\u53ca\u793e\u4f1a\u7684\u613f\u666f\uff0c\u8fc5\u901f\u63a8\u52a8\u7ec6\u80de\u4e0e\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u7684\u7814\u53d1\u4e0e\u4e34\u5e8a\u5e94\u7528\u3002\u4f5c\u4e3a\u9886\u5148\u7684\u7ec6\u80de\u4e0e\u57fa\u56e0\u6280\u672f\u5e73\u53f0\u578b\u516c\u53f8\uff0c\u8363\u6cfd\u96c6\u56e2\u4e0b\u4e00\u6b65\u5c06\u4e0e\u591a\u4e2a\u6d77\u5916\u5408\u4f5c\u4f19\u4f34\u5206\u4eab\u5176\u4ea7\u54c1\u7ba1\u7ebf\u7684\u5168\u7403\u5408\u4f5c\u6743\u76ca\uff0c\u540c\u65f6\u534f\u540c\u5f00\u5c55\u5168\u7403\u591a\u4e2d\u5fc3\u4e34\u5e8a\uff0c\u4f9d\u6258\u5176\u5728\u7ec6\u80de\u4e0e\u57fa\u56e0\u9886\u57df\u5185\u5f3a\u5927\u7684\u6280\u672f\u8f6c\u5316\u80fd\u529b\u4e0e\u4e34\u5e8a\u8d44\u6e90\u4f18\u52bf\uff0c\u9020\u798f\u66f4\u591a\u96be\u6cbb\u6027\u91cd\u5927\u75be\u75c5\u60a3\u8005\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"

2021\u5e746\u67088\u65e5\uff0c\u56fd\u5185\u9886\u5148\u7684\u7ec6\u80de\u4e0e\u57fa\u56e0\u6280\u672f\u5e73\u53f0\u578b\u516c\u53f8\uff0c\u676d\u5dde\u8363\u6cfd\u751f\u7269\u79d1\u6280\u96c6\u56e2\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u8363\u6cfd\u96c6\u56e2\u201d\uff09\u62df\u9996\u6b21\u516c\u5f00\u53d1\u884c\u80a1\u7968\u5e76\u5728\u5883\u5185\u8bc1\u5238\u4ea4\u6613\u6240\u4e0a\u5e02\uff0c\u76ee\u524d\u5df2\u540c\u56fd […]<\/a><\/p>\n<\/div>","protected":false},"author":27,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[119],"tags":[],"class_list":{"0":"post-25038","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-bio-pharmaceuticals"},"_links":{"self":[{"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/posts\/25038","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/comments?post=25038"}],"version-history":[{"count":0,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/posts\/25038\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/media?parent=25038"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/categories?post=25038"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ibnews.com\/cn\/wp-json\/wp\/v2\/tags?post=25038"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}